Goriounova Lab

Research focus

ERC Consolidator Grant · 2025

Understanding the specialized function of human neurons and circuits

Human cognition stands out from other species, but how neurons and circuits in the human brain support cognition is poorly understood. Our recent work showed that human brain holds specialized neuron types – pyramidal neurons in cortical layer 3 (L3 PNs) – with distinct properties that associate with IQ scores. In the human brain, L3 PNs form circuits with each other and another human-specialized interneuron type, double bouquet cell (DBC). These circuits might be critical for human cognition as they are selectively lost in cognitive disorders, but their function in the human brain is unknown. In addition, our data show that human L3 PNs are modulated in a distinct manner by a metabotropic…

From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.