ERC Consolidator Grant · 2025
Role of Border-Associated Macrophages in neurocognition
The field of neuroimmunology is rapidly advancing, revealing that the brain does not function alone; immune cells play a significant role in modifying our behaviour in health and disease. While the brain itself lacks most immune cell types apart from microglia, the question arises: how do immune cells communicate with neurons and influence brain function? Interestingly, recent data indicate that the brain borders contain a massive network of immune cells, including border-associated macrophages (BAM). Using innovative depletion strategies based on transcranial drug delivery in mice and genetic models targeting BAM, my team discovered that in the absence of BAM, proliferation and activation…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.
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