ERC Starting Grant · 2025
Defining the function of nodes of Ranvier as regulatory units of the white matter
The human brain is divided into the grey matter and the white matter (WM). The grey matter includes the synapses which are paramount for processing information, while the WM consists of myelinated axon bundles that conduct information between different brain areas. Brain information processing relies heavily on precise spike timing. This raises questions about the preservation of spike-encoded timing information as it propagates across WM axons, which can extend tens of centimetres before reaching synapses. My research challenges the view that myelinated axons merely serve as electrical conduits in the brain and proposes that the WM contains regulatory units essential for processing…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.