Squair Lab

University Hospital of Lausanne – CHUV

- · Switzerland

ERC-funded
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Research focus

ERC Starting Grant · 2025

Mechanism-driven neuroprosthetics to restore hemodynamic stability in parkinsonian syndromes

About 1 million people with Parkinson’s disease live in the EU, including those with atypical parkinsonian syndromes. Up to 50% of them suffer from severe hypotensive symptoms, which include debilitating episodes of fatigue, nausea, and syncope. These complications are a significant cause of morbidity as they decrease mobility, increase the incidence of falls, reduce quality of life, and increase the risk of stroke. We recently developed a neurosurgical approach that applies epidural electrical stimulation (EES) over the thoracic spinal cord to prevent hypotension in people with spinal cord injury, and also demonstrated proof of concept in one patient with multiple system atrophy. While…

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