ERC Starting Grant · 2025
Disentangling self-paced from cued action initiation in the motor thalamus
The initiation of movement, whether triggered by an internal (self-paced) or external stimulus (cued), relies on complex neural circuitry involving the pre-motor and motor cortex, basal ganglia, cerebellum, midbrain, and thalamus. The motor thalamus (mThal) integrates inputs from these structures to orchestrate the shift of cortical activity from a preparatory into an execution mode, resulting in action initiation. However, it is unclear whether the activity in the mThal that releases the motor program is different for externally cued and self-paced movements. Projections from the cerebellum and from the midbrain to the mThal have a critical role in cued movement initiation, while…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.