ERC Starting Grant · 2016
Investigating Host-Microbial Interactions after Bariatric Surgery
Obesity and related co-morbidities give rise to severe health and socioeconomic problems. Surgical treatment for obesity (bariatric surgery) is remarkably effective in the control of morbid obesity and rapid resolution of Type 2 Diabetes, and the number of such procedures is increasing rapidly in many obesity-prevalent countries. We, and others, have demonstrated that surgical interventions such as Roux-en-Y Gastric Bypass (RYGB) modulates gut hormone levels, induces systemic metabolic changes and results in the shift of the microbiome from Firmicutes to the Proteobacteria phylum. Although the gut microbiota have been implicated in the reduction of adiposity post-surgery, the long-term…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.