Schrauwen-Hinderling Lab

Maastricht University

Zuid-Nederland (NL4) · Netherlands

ERC-funded
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Research focus

ERC Starting Grant · 2017

Novel methods in Magnetic Resonance Spectroscopy to investigate mechanisms underlying metabolic disease

The high prevalence of obesity-related metabolic disease such as diabetes and cardiovascular disease urgently requires earlier interventions in the pathogenesis of these diseases and the identification of new therapeutic targets that work in humans. To show the human relevance of mechanistic information gained from rodent and cell studies on the pathogenesis of insulin resistance and diabetes, human translational research is needed. Non-invasive techniques are key in human translational research. Magnetic Resonance Spectroscopy (MRS) is used in metabolic research, e.g. to determine ectopic lipids, but its potential is far from fully explored, and novel, dedicated MRS sequences can be…

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