Rinkevich Lab

Research focus

ERC Consolidator Grant · 2018

A WORLD WITHOUT SCARS: Regenerating wounded skin rather than patching with scars

Scars are a mystery. They rarely develop in lower vertebrates, where the norm is a complete regeneration of damaged tissues, but are frequent in mammals including humans. Scar phenotypes depend on different injury types, anatomic locations, age, gender and species. The natural diversity of scars includes rare cases, where damaged tissues regenerate without scarring. The scar/regeneration decision remains unresolved and scar prevention is a clinical challenge. Current research has been held up by conceptual and operational bottlenecks. The current conceptual notion comes from experiments showing that scarring depends on the internal environment of the injured organ. I challenged this notion…

From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.