ERC Advanced Grant · 2020
Metabolic mechanisms underpinning obesity-driven pancreatic cancer
Pancreatic cancer is one of the most lethal malignancies, showing a high rate of metastatic spread and a dismal prognosis. With almost no effective treatment options, new therapies to treat this devastating disease are urgently needed. Such advances will depend on a better understanding of the mechanisms that drive pancreas cancer progression. Previous work has revealed two interesting features of pancreas cancer on which this proposal is built. Firstly, pancreas cancers contain an extremely high stromal component – normal cells that become part of the tumour mass and contribute to the control of malignant progression. Secondly, obesity – a rapidly growing epidemic worldwide – is associated…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.