ERC Consolidator Grant · 2020
Tumor-lock: forbid the generation of circulating tumor cells
One woman in eight is destined to develop breast cancer. All women that lose their battle against breast cancer vividly realize that its most deadly feature is not the primary lesion, but its ability to spread to distant sites and become an incurable, metastatic disease. In this proposal, we aim to address what is arguably the most ambitious challenge in the cancer field: metastasis prevention. Metastatic spread of cancer occurs through the generation and hematogenous dissemination of circulating tumor cells (CTCs). We recently discovered that CTCs are heterogeneous, and that CTC clusters – multicellular aggregates of cancer cells and immune cells in circulation – represent the most…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.
← All labs at Swiss Federal Institute of Technology Zurich (ETH Zurich)