ERC Starting Grant · 2021
Functional Measurements IN-THE-KIDNEY to Diagnose, Understand and Treat Renal Tubulopathies
BACKGROUND | Renal tubulopathies are a large group of genetic disorders that disturb the function of the kidney tubule. A major challenge for diagnostics and treatment of magnesium (Mg2+) wasting tubulopathies, is absence of functional cell models and tools to study the pathophysiology. Diagnostics of hereditary Mg2+ wasting tubulopathies based on genetic screening, rather than biological measurements of kidney processes. Therapy largely depends on oral supplements because therapeutics that target the cause of disease are not available. VISION | In my vision, better insights in the cellular functional processes in the kidney are the next essential step forward towards better diagnostics,…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.