ERC Consolidator Grant · 2023
HUNTING GHOST NEURONS IN THE NEUROENDOCRINE HYPOTHALAMUS
The hypothalamus contains heterogeneous neurons that dictate behaviours and physiological functions through cross-talk mechanisms with peripheral hormones. Neuronal diversity is the key to enabling hypothalamic functions and, according to the neuroscience dogma, is mainly preset during embryonic life. But what if this model is incorrect? Can neuronal heterogeneity be plastically modulated throughout adult life as well? Here, based on my published work and solid preliminary results, I propose that special 'Ghost' neurons in the hypothalamus display plastic mechanisms of cell-identity reprogramming to accommodate neuroendocrine functions in adult life under physiological conditions. Such…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.
← All labs at National Institute of Health and Medical Research (INSERM)