ERC Consolidator Grant · 2023
Early detection, molecular mechanisms and therapeutic interventions in chronic kidney disease
The objective of ELIMINATE-CKD is to demonstrate that combining measures of kidney structure and function will strongly enhance detection of chronic kidney disease (CKD). To reach this objective, I will develop a new method to quantify the number of nephrons, the smallest functional units in the kidney. Rationale: - CKD affects ~10% of the global population and causes 2.6 million deaths/year. CKD-associated costs (140 billion euros/year in Europe) exceed diabetes and cancer. Limitations in CKD detection impede the success of emerging therapies. - Current CKD definition is based on creatinine-based estimated glomerular filtration rate, which is often inaccurate due to interindividual…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.