Delloye-Bourgeois Lab

Research focus

ERC Starting Grant · 2023

Decrypting neuro-cancer crosstalk in pediatric cancers of the peripheral nervous system

Cancer neuroscience has emerged as a major axis of cancer biology, at the crossroad of two biological areas. Multi-layered dialogs between cancer and nervous contingents have started to be unravelled, with pivotal roles of the nervous system in tumor initiation, growth and invasion, in turn amplified by cancer-induced hijacking of nervous functions. Specifically, brain tumors were shown to be integrated in bona fide neuron-to-cancer synaptic networks but also to capture neural-activity dependent released factors that boost their tumor properties. In the last years, this completely rewired the view of high-grade gliomas, especially those arising in the pediatric population, suggesting…

From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.