ERC Starting Grant · 2024
Functional characterization of the colorectal cancer metastasis microbiome
Host cells and microbial inhabitants form an intricate ecosystem in the human body, extensively influencing host phenotypes in health and disease. Despite much progress in sequencing-based cancer microbiome research, elucidating functional roles of bacteria in metastasis formation remains an important unsolved challenge. In the METABAC project, we will explore such bacterial roles as drivers of colorectal cancer metastasis. We will investigate new concepts on whether bacteria can equip cancer cells with malignant features, migrate within the host and potentially represent targets for cancer therapy. In Aim 1, my group will characterize the microbial inhabitants of colon tumors and…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.