Vandeputte Lab

Research focus

ERC Starting Grant · 2024

CoRe Defense: fortifying the resident gut microbiota’s colonization resistance to combat intestinal bacterial infections.

Currently, we rely on antibiotics to combat potentially life-threatening gastrointestinal (GI) bacterial infections. However, the susceptibility to infection and the severity of symptoms can vary significantly among individuals exposed to the same pathogen.1–3 If we could unravel the factors responsible for differences in infection susceptibility, we could formulate strategies to reduce the incidence of symptomatic infections, ultimately saving lives and reducing the need for antibiotics. Traditionally, researchers have approached this puzzle from two main perspectives: a human-centered view, delving into the intricacies of the host immune system, or a pathogen-centered view, scrutinizing…

From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.