Greco Lab

Humanitas University

Nord-Ovest (ITC) · Italy

ERC-funded
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Research focus

ERC Starting Grant · 2024

DeCiphering Systemic Diurnal MetabOlism and EnDocrinE Signaling in HEART Failure

Heart failure (HF), the ultimate outcome of many cardiovascular pathologies, imposes a significant global health and economic burden while remaining associated with high mortality rates. There is therefore an urgent need for innovative approaches to comprehensively understand and treat HF. Most HF research, has thus far focused on the pathophysiology of the heart, only partially covering the role of non-cardiac organs, despite HF being a complex multiorgan syndrome. The extent to which extra-cardiac organs, particularly those playing a key role in metabolism control, contribute to HF remains largely unknown. CODE-HEART aims to bridge this knowledge gap by focusing on metabolic interorgan…

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