ERC Consolidator Grant · 2025
Mapping White Adipose Tissue lipid UPtake to cardiovascular disease initiation
Obesity is associated with adipose tissue dysfunction and greatly increased risk for developing not only metabolic pathologies but also cardiovascular disease (CVD). While insulin resistance and adipose-derived cytokines are established drivers of vascular dysfunction and atherosclerosis initiation, the direct contribution of changes in white adipose tissue (WAT) lipid uptake on vascular health has remained unresolved, yet would open up novel treatment opportunities. My lab has built an arsenal of unique transgenic mouse models and organotypic human in vitro systems for mapping WAT lipid dynamics, yielding exciting preliminary data and the opportunity for us to now address this key…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.