Najumudeen Lab

University of Helsinki

Manner-Suomi (FI1) · Finland

ERC-funded
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ERC Consolidator Grant · 2025

How do cells absorb nutrients: Spatially resolving nutrient uptake using intestinal cells as a paradigm

Cells need a constant supply of nutrients to maintain homeostasis, integrity and identity. In multicellular organisms, cells of different types tightly control this chemical exchange with their environment depending on metabolic requirements. While intracellular metabolic and nutrient-sensing pathways are widely studied, our understanding of how cells regulate their nutrient uptake in the first place remains largely unexplored. Nutrient uptake occurs at the cellular membranes via transporter proteins. In this context, I recently identified a case where a solute carrier (SLC) transporter controls intestinal cancer cell growth and metastasis to distant organs. Considering the intestine is the…

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