ERC Consolidator Grant · 2025
Appetite and Obesity: leveraging the power of dog genetics for biomedical insight.
Epidemic obesity threatens global health and has been attributed to changes in diet and lifestyle. However, not everyone gains weight in an obesogenic environment. Heritable variation in appetite renders some individuals susceptible to weight gain, but which genes are responsible and why, and what overlap is there between appetite and obesity genes? I study pet dogs to identify genes and molecular mechanisms underlying obesity, with the overarching aim of reducing the impact of obesity on human (and animal) health. Fat mass and appetite vary widely between individual and breeds of dog and their genetic architecture simplifies trait mapping. This makes dogs a compelling animal model in which…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.