ERC Starting Grant · 2025
Spatiotemporal regulation of metastatic breast cancer cell fate
Breast cancer is the most common malignancy in women with globally over 600’000 deaths per year. While cancer diagnosis before metastasis is often associated with a favourable prognosis, due to surgical and new therapeutic approaches, once metastasis is initiated, the survival rates decline significantly. However, the understanding of this last and most detrimental phase of cancer remains at a low resolution, reflected by the lack of metastasis-targeted therapeutic options. In fact, most of the studies have focused on the understanding of primary tumour states and their relationship to metastasis. Recently, it has emerged, however, that secondary seeding from metastatic deposits to new…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.