ERC Starting Grant · 2016
Mechanisms of Regeneration Initiation
Injury poses a key threat to all multicellular organisms. However, while some animals can fully restore lost body structures, others can only prevent further damage by mere wound healing. Which molecular mechanisms determine whether regeneration is induced or not is an unsettled fundamental question. I will use whole body regeneration, one of the most fascinating biological processes, as an experimental paradigm to identify the mechanisms of regeneration initiation. As a model organism I will employ planarians, flatworms with extraordinary plasticity that regenerate every piece of their body within a few days. I will mechanistically dissect how these animals rapidly induce an efficient…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.
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