Nowack Lab

Flanders Institute for Biotechnology (VIB)

Vlaams Gewest (BE2) · Belgium

ERC-funded
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ERC Consolidator Grant · 2019

Dissecting the molecular mechanisms that execute developmental programmed cell death in plants

Programmed Cell Death (PCD) is fundamental to the development and health of multicellular organisms. However, our knowledge on developmentally controlled PCD in plants remains fragmentary, despite its undoubted significance for plant growth and reproduction. My team has established the Arabidopsis root cap as a novel model system for developmental PCD in plants. This model has enabled us to identify a gene regulatory network controlling the preparation of PCD. However, the molecular processes that terminate the vital functions of a plant cell during the final steps of PCD execution remain unknown. Exploiting the accessibility of the root cap for live-cell analysis of PCD execution, we…

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