ERC Starting Grant · 2019
Metabolic Coupling During Bacterial Development
Studies on developmental biology have traditionally focused on deciphering the signaling and the regulatory networks that control cellular differentiation. However, the means by which the interplay between developmental regulatory circuits and housekeeping metabolism contribute to determine the fate of differentiating cells is poorly understood. Here, I aim provide a comprehensive analysis of the role of housekeeping metabolic functions during endospore formation in the bacterium Bacillus subtilis. Sporulation is a simple developmental pathway that entails the interaction between two cells arising from a single cell division: the forespore, which becomes the metabolically dormant spore, and…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.