Bellaiche Lab

Research focus

ERC Advanced Grant · 2020

Developmental scaling of cell mechanosensitivity in epithelial tissue

All biological systems tailor their organization and properties to their size. Such size scaling is essential to The scaling of biological structures and substructures with their size is a preeminent and essential feature of life. Accordingly, the study of scaling properties had a profound impact on our understanding of animal physiology, gene expression, cell cycle regulation and intracellular dynamics. Their study at the cell level has often led to the discovery of the fundamental mechanisms allowing cells to probe their size or geometry (cell size ruler). Yet we are very far from understanding how such cell size ruler controls more macroscopic processes such as morphogenesis or global…

From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.