Moor Lab

Research focus

ERC Consolidator Grant · 2025

Unraveling the Life Cycle of Metastatic Cells from Invasion to Outgrowth.

Colorectal cancer (CRC) is the second leading cause of cancer-related mortality worldwide, accounting for nearly 10% of cancer-related deaths. The majority of CRC-related deaths result from metastatic dissemination, with the liver and lung being the most frequent distant sites of metastasis. Effective therapies to prevent metastatic CRC progression are lacking. This gap stems from our limited understanding of the cancer-intrinsic and tumor microenvironmental factors that drive advancement through each intermediate step of the metastatic cascade. Here, we will use systems approaches to unravel the life cycle of metastatic cells, focusing on cancer cell plasticity and interactions with host…

From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.