Bedzhov Lab

Max Planck Society

Bayern (DE2) · Germany

ERC-funded
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ERC Consolidator Grant · 2021

The Sleeping Embryo

The implantation of the blastocyst into the uterine wall is a key step of the reproductive cycle, which mediates the connection of the embryo to the maternal tissues during the early stages of pregnancy. However, in some species, including the house mouse, this process can be put on hold, while the embryo falls into a reversible state of suspended animation, known as diapause. The dormant embryos can reside in a “deep sleep” over extended periods of time (e.g. bypassing unfavourable environmental conditions), without compromising their developmental potential. Although, the maternal hormonal control of implantation and the process of transient mouse embryogenesis have been intensively…

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