Galli Lab

Research focus

ERC Starting Grant · 2021

Timing cell cycles in multicellular development

Animal development depends on precisely timed cell divisions, which ensure the formation of tissues and organs with specific architectures and functions. As cells differentiate and mature, they need to modify the expression of cell-cycle regulators in order to achieve tissue-specific division patterns. It is largely unknown how cells coordinate cell-cycle gene expression changes with developmental timing and how cell cycles can be altered to give rise to different tissue architectures and organ sizes. DevCycle will address these questions by studying intestinal cell cycles in nematodes. I have recently pioneered tools to measure mRNA expression changes and chromatin modifications in…

From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.