ERC Consolidator Grant · 2024
Mucociliary adaptations and gut microbiome establishment in Xenopus
Cell type compositions determine tissue morphologies and functions, are adapted during evolution, and their changes cause diseases. However, we do not understand how cell type compositions can be controlled and modified to predictively achieve different organ functions. The goal of the MAGIX project is to understand the developmental mechanisms controlling cell type compositions, and to mechanistically link variations of cell type compositions to physiological properties of tissues in development and disease. We will use mucociliary epithelia as they provide an optimal system to study how adaptations of cell type compositions are regulated and how they determine organ functions. They build…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.