ERC Consolidator Grant · 2024
Spatial and temporal regulation of cell competition
Every tissue in our body is a mosaic formed by individual cells that have different levels of cellular fitness. Competitive interactions, where the relative differences in fitness determine cell survival, therefore have a major impact on the physiology of a wide variety of tissues. Cell competition is versatile and abundant, and it impacts a broad spectrum of processes, ranging from early embryonic development to aging. Yet, due to the heterogeneity of competitive interactions, both in space and time, the dynamics of this process are difficult to unravel. For instance, it is unclear which long-term adaptations of cellular behavior cell competition induces. Furthermore, the consequences of a…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.