ERC Starting Grant · 2024
Collective Regulation of Cell Decisions
Developing systems show an unmatched complexity due to an entangled regulation across different levels of organization. Errors in this regulation often lead to tissue and organ malformations and disease. Accordingly, cell decisions like division, fate or motility are not only guided by local signals generated at the cell micro-environment, but also integrate cues propagated by collective properties at the tissue-level, such as tissue rigidity. How the cell’s macro-environment impacts cell decisions is still elusive, largely because we lack methods and concepts to identify and eventually control collective tissue properties. I will tackle this question by harnessing the physics of collective…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.