ERC Starting Grant · 2025
Uncovering the function of novel cytoskeletal polymers in the extreme mechanics of eukaryotic cells
The ability of eukaryotic cells to generate and resist mechanical forces, locomote and spatially organize their subcellular structures relies on the cytoskeleton. The hallmark of cytoskeletal proteins is their ability to polymerize into filaments, which in turn organize into cellular-scale networks that support a variety of functions that require the generation of mechanical force. Decades of work have significantly increased our knowledge of the composition and mechanisms of force generation by networks of actin, tubulin and intermediate filaments. In contrast, the mechanisms and function of cytoskeletal networks, whose primary component is centrin remain unexplored. Centrins are conserved…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.
← All labs at Swiss Federal Institute of Technology Lausanne (EPFL)