ERC Starting Grant · 2025
Translation Control in Development: when, where and how
The translation of mRNAs by ribosomes is a key step in decoding the information stored in our genome. Animal development requires a strict regulation of translation, in particular when transcription is absent, as in most early embryos. A range of mechanisms ensure that mRNAs are translated with the right efficiency and location, in the right cell types and exactly when their protein products are needed. Disruption of this regulation can lead to developmental defects and embryonic lethality. Despite the recognized importance of translation regulation, the impact of translation regulation, and especially localized translation, on protein levels remains largely unknown for most genes.…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.