Brückner Lab

University of Basel

- · Switzerland

ERC-funded
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ERC Starting Grant · 2025

Information flow in developmental cell fate patterning

Embryonic development relies on the ability of multi-cellular systems to collectively coordinate the establishment of precise spatial patterns of cell fates. An inevitable obstacle to such coordination is intrinsic noise at the single-cell level, which constrains the amount of information accessible to cells for fate decisions. While such information was often considered to be encoded in overall concentrations of extracellular signals, it is becoming increasingly clear that cells use a much broader set of inputs to make decisions. In this project, we will develop a new data-driven theoretical framework of developmental patterning to quantify, characterize and predict how cells generate and…

From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.

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