ERC Advanced Grant · 2024
DNA-binding domain Conditioned Precision Genome Editing
Genome editing in human therapies has the potential to revolutionize modern medicine. With numerous clinical trials underway and the recent approval of the first genome editing therapy, the field is rapidly advancing. However, there is a consensus that clinical genome editing tools must be efficient, precise and safe. Current tools predominantly rely on host cell DNA repair pathways to complete the editing process, which poses a risk for unintended editing events. Host cell DNA repair independent, fully programmable editing tools represent a new class of genome editing technologies, significantly expanding the potential for delivering life-saving therapies to patients. Genome editing tools…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.