Ohm Lab

Utrecht University

West-Nederland (NL3) · Netherlands

ERC-funded
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ERC Starting Grant · 2016

Functional genomics in Schizophyllum commune: leveraging the diversity in this hypervariable fungus to understand mushroom development

Mushrooms are the sexual reproductive structures of basidiomycetes. Much remains to be learned about the molecular regulation of mushroom development. Only a few genes have been implicated in this process, but their exact function remains unknown. Schizophyllum commune is a model system for mushroom-forming fungi. It was recently shown that this species shows the highest intraspecies DNA variability in eukaryotes with 150 SNPs per 1000 base pairs, yet they can still reproduce sexually. This hypervariabity is also illustrated by variability in the response to environmental factors that initiate mushroom development and by the differences in morphology within this species. I propose a…

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