Dima Lab

Research focus

ERC Starting Grant · 2016

A genomics and systems biology approach to explore the molecular signature and functional consequences of long-term, structured fasting in humans

Dietary intake has an enormous impact on aspects of human health, yet scientific consensus about how what we eat affects our biology remains elusive. To address the complex biological impact of diet, I propose to apply an unconventional, ‘humans-as-model-organisms’ approach to compare the molecular and functional effects of a highly structured dietary regime, specified by the Eastern Orthodox Christian Church (EOCC), to the unstructured diet followed by the general population. Individuals who follow the EOCC regime abstain from meat, dairy products and eggs for 180-200 days annually, in a temporally-structured manner initiated in childhood. I aim to explore the biological signatures of…

From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.