ERC Consolidator Grant · 2017
Metabolism of a cell pictured by single-cell approach
Every cell is unique. Metabolites define the composition of each cell and play key roles in essential intracellular processes of energy production and uptake, signaling, regulation, and cell death. Obtaining metabolite signatures of individual cells and linking them to cellular phenotypes is of paramount importance for a holistic understanding of these processes. This requires high-throughput single-cell metabolomics that is not generally attainable due to the limited sensitivity, low throughput, and disruptiveness of state-of-the-art metabolomics methods. I propose to develop a spatial single-cell metabolomics approach for human cell culture systems. The approach will be based on using…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.