ERC Consolidator Grant · 2025
Scales of Mitochondrial Stress Response
The increase in human life expectancy and associated rise in late-life morbidities will be a key societal challenge of this century. Cellular homeostasis dwindles over time and the cellular structure tied to aging and age-related diseases like no other is the mitochondrion. As the sole endosymbiotic organelles of the human cell, mitochondria must elaborately interface with their environment—inside the cell and beyond—for the effective detection, communication and resolution of mitochondrial dysfunction. Until recently, a systematic and in-depth study of mitochondrial stress responses was infeasible in the human system, but our work has now created an opportunity for their decryption.…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.