ERC Starting Grant · 2018
Dissecting epistasis for enhanced crop productivity
A major goal in plant biology is to understand how naturally occurring genetic variation leads to quantitative differences in economically important traits. Efforts to navigate the genotype-to-phenotype map are often focused on linear genetic interactions. As a result, crop breeding is mainly driven by loci with predictable additive effects. However, it has become clear that quantitative trait variation often results from perturbations of complex genetic networks. Thus, understanding epistasis, or interactions between genes, is key for our ability to predictably improve crops. To meet this challenge, this project will reveal and dissect epistatic interactions in gene regulatory networks…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.