ERC Starting Grant · 2020
Cross-omics integration to identify modulators for improving vaccine efficacy
Influenza is a significant public health threat and vaccines are crucial for preventing infections at population-level. The efficacy of vaccination per individual, however, is highly variable. The causes for this broad variability in vaccine response between individuals remain poorly understood. In this proposal, I hypothesize that genetic variants and their downstream pathways underlie the heterogeneity in vaccine response between individuals. This ERC project aims to for the first time, systematically investigate the interactions between genetic, non-genetic host and environmental factors, and the response to vaccination in order to build reliable models for predicting vaccine efficacy.…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.