Schirmer Lab

Technical University of Munich

Bayern (DE2) · Germany

ERC-funded
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ERC Starting Grant · 2021

Hormone-microbiome interactions as a key-player in female health

Incidence rates of inflammatory and autoimmune diseases are increasing dramatically and a clear sex bias exists in disease presentation and progression. While the underlying reasons are largely unknown, hormones are hypothesized to play a central role in these discrepancies and the microbiome is linked to disease pathology. However, a key understudied player is the interplay between hormones and the microbiome in human health. Crucially, hormone-microbiome interactions in the human body are poorly understood. Microbes produce hormone-like signals and play a role in hormone metabolism and regulation, while hormones influence bacterial growth. It is currently unknown how the menstrual cycle…

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