ERC Consolidator Grant · 2023
RNA structure ensemble dynamics in living cells
Ribonucleic acid (RNA) is a Ribonucleic acid (RNA) is a jack-of-all-trades. It orchestrates and contributes to a multitude of essential cellular processes, both under physiological and pathological conditions. Among these, transcriptional and post-transcriptional regulation of gene expression, splicing, and translation control. Many of the functions of RNA rely on its ability to fold into stable secondary structures. However, RNA structures are far from being static. Indeed, for a given RNA, multiple alternative structural conformations can coexist as part of a heterogeneous and dynamic ensemble. Crucial to the regulatory functions of RNA structures is their ability to dynamically…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.