ERC Consolidator Grant · 2023
Mechanisms and biological functions of H3K27me3 reprogramming in plant microspores
How totipotency is established in germ cells is an essential question in reproductive biology. In the plant male germline, the haploid meiotic products – microspores – are totipotent, which permits crop breeding via microspore embryogenesis. However, the molecular basis and biological significance of microspore totipotency are unknown. More generally, our understanding of plant cell totipotency is in its infancy. My lab established the Arabidopsis male germline as a model to study germline epigenetic reprogramming. We recently discovered that H3K27me3, a histone modification essential for developmental regulation, is globally erased in microspores. We also identified a new family of histone…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.