Browne Lab

National University of Ireland - University College Cork

Ireland (IE0) · Ireland

ERC-funded
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Research focus

ERC Starting Grant · 2023

SYNergize: Understanding spore-forming gut bacteria biology to target pathogens

Our intestinal microbiota consists of a dense community of microorganisms, highly adapted to the human gastrointestinal tract. Shared species between individuals indicates the presence of evolved and efficient transmission routes that ensure colonisation of beneficial bacterial species. Research has traditionally focussed on blocking enteric pathogen transmission routes as a means to prevent disease. However, a greater focus on understanding the transmission routes of commensal gut bacteria is required to promote health. Spores are resilient structures that maintain bacterial integrity in a dormant state for extended periods. My previous work has shown that spore-formation is a prevalent…

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