Zimmermann-Kogadeeva Lab

European Molecular Biology Laboratory (EMBL)

Baden-Württemberg (DE1) · Germany

ERC-funded
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ERC Starting Grant · 2023

Resolving metabolic interactions between the gut microbiota and the host with multi-omics-based modelling

The gut microbiota is essential to human health: microorganisms in the human body help to digest nutrients, engage in host metabolism, immunity, behaviour and brain functions. Since the gut microbiota, in contrast to the human genome, can be modified through dietary and therapeutic interventions, modulating the microbiota is a promising path to improve human health and to prevent or treat diseases. However, predicting the effects of microbiota perturbations on the host metabolic phenotype remains extremely challenging due to our limited understanding of bacterial metabolic functions, molecular interactions within microbial communities, and the mechanisms of microbial interactions with the…

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