ERC Starting Grant · 2023
How to evolve without centromeres: meiotic recombination dynamics in holocentric plants
Centromeres strongly affect genomic architecture and meiotic recombination distribution and also play a key role in constraining karyotype evolution. The recombination landscape is also heavily influenced by chromosome number and structure (i.e., karyotypes), as at least one crossover per chromosome (and rarely more than three) occurs in most species, making chromosome number the primary driver of recombination frequency. In addition, centromeres inhibit recombination, and therefore crossovers tend to occur mostly at chromosome ends. However, several unrelated eukaryotic lineages do not have centromeres, or at least, not conventional ones. Such is the case for plants with holocentric…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.