Drinnenberg Lab

Research focus

ERC Consolidator Grant · 2024

The impact of chromatin on genome organisation, function and evolution

Chromatin contributes to many important processes ensuring the proper functioning of eukaryotic cells. In addition, it shapes linear and spatial genome organisation, and specifies chromosomal regions including centromeres that play a key role for chromosome segregation. Chromatin-associated factors also fold the genome in 3D to enable the transfer of chromosomes during mitosis or to regulate gene expression. Chromatin composition is however not identical among eukaryotes. How differences in chromatin composition contribute to different linear and spatial genome organisations is largely unknown. We aim to address these unknowns in three non-overlapping aims focusing on Lepidoptera and other…

From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.