Bonaguro Lab

Research focus

ERC Starting Grant · 2024

Understanding the impact of environmental POLlution on the adaptive Immune System

There is growing evidence that currently used toxicological assessments of chemicals fail to fully capture their actual biological activity. While chemicals are routinely tested for acute toxic effects, often at high concentrations, potential function-modulating effects at low concentrations are often underexplored. The inclusion of up-to-date high-resolution methods in the toxicological screening praxis would allow instead to fully capture the complex bioactivity profile of these compounds, which depends on numerous aspects including bioavailability, route of exposure and individual susceptibility. While the last 100 years have seen an enormous number of chemicals introduced into our daily…

From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.