ERC Starting Grant · 2024
Cancers are proliferative outgrowths of abnormal cells driven by a selfish evolutionary programme. Most cancers arise from and remain within the bodies of their respective host individuals. Rarely, however, cancers may escape their hosts to become ‘transmissible cancers’, infectious cell lineages that spread between individuals by direct transfer of cancer cells. As parasitic cancers capable of surviving for millennia, transmissible cancers offer a unique model for exploring how mutation, selection and cellular processes mould and constrain selfish tumour evolution. Marine bivalves (shellfish including clams, mussels and cockles) are affected by at least 10 transmissible cancers, which…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.